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The current treatment regimen for Lyme disease is typically a course of antibiotics, such as doxycycline, amoxicillin, or cefuroxime axetil, given for 14 to 21 days. In more severe cases, intravenous antibiotics may be necessary. The specific antibiotic and duration of treatment will depend on the stage of the disease and the patient's symptoms. In addition to antibiotics, over-the-counter pain relievers may be used to alleviate pain and fever. It is important to note that early diagnosis and treatment of Lyme disease is crucial to prevent complications.

If left untreated, Lyme disease can lead to a variety of long-term complications, including:
  • Chronic Lyme disease: Some individuals may continue to experience symptoms such as fatigue, muscle and joint pain, and neurological problems even after completing antibiotic treatment.
  • Neurological complications: These can include peripheral neuropathy (nerve damage in the limbs), Bell's palsy (facial muscle weakness), and meningitis.
  • Arthritis: This can occur in the larger joints, such as the knee, and can be accompanied by joint swelling and stiffness.
  • Cardiac complications: Lyme disease can cause inflammation of the heart muscle and its surrounding sac, leading to conditions such as Lyme carditis.
  • Cognitive problems: Some individuals may experience memory problems, difficulty with concentration, and other cognitive difficulties.
It's important to note that these complications are rare, and most people who are treated for Lyme disease make a full recovery. Again, early diagnosis and prompt treatment can help prevent these complications from developing.
 
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